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Schematic representation of peptide, linker and drug in the peptide-drug conjugates
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|---|---|---|---|---|
| XHWSYKLRPG | glutaric acid | Doxorubicin |
| Identification | |
|---|---|
| ConjuPepDB ID | cpd01562 |
| Smiles | |
| Molecular weight | 1943.87 |
| Molecular formula | C95H121N19O26 |
| Chemical name | Peptide information |
| Sequence (one letter) | XHWSYKLRPG |
| Length | 10 |
| Peptide name | N/A |
| External ID | |
|---|---|
| CAS number | 179910-83-9 |
| Other information | |
|---|---|
| Application | REVIEW |
| Conjugate type | amide |
| Linker | N/A |
| Linker Type | glutaric acid |
| Small molecule | Doxorubicin |
| Small molecule CAS | 23214-92-8 |
| Calculated properties | |
|---|---|
| LogP | -2.63587 |
| Rotatable bonds | 48 |
| H bond donor | 22 |
| H bond acceptor | 30 |
| Polar surface area (PSA) | 690.59000 |
| Citations | |||||
|---|---|---|---|---|---|
| ID | Title | Year | Authors | Journal | DOI |
Cancer chemotherapy based on targeting of cytotoxic peptide conjugates to their receptors on tumors | 1999 | Schally, Andrew V.; Nagy, Attila | European Journal of Endocrinology | ||
