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Schematic representation of peptide, linker and drug in the peptide-drug conjugates
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|---|---|---|---|---|
| GKX | hexanamide | Tetraphenyl porphyrin (TPP) derivative |
| Identification | |
|---|---|
| ConjuPepDB ID | cpd01561 |
| Smiles | |
| Molecular weight | 1366.63 |
| Molecular formula | C81H82N12O9 |
| Chemical name | Peptide information |
| Sequence (one letter) | GKX |
| Length | 3 |
| Peptide name | tripeptide |
| External ID | |
|---|---|
| CAS number | 171290-86-1 |
| Other information | |
|---|---|
| Application | Synthesis, controlled attachment of porphyrins to peptides and other compounds |
| Additional function | Diagnosis, contrast enhancement agents in magnetic resonance imaging (MRI) |
| Pharmacological class | other |
| Conjugate type | amide |
| Linker | N/A |
| Linker Type | hexanamide |
| Small molecule | Tetraphenyl porphyrin (TPP) derivative |
| Small molecule CAS | 67605-64-5 |
| Structure method | 1H NMR, COSY |
| NMR solvent | CDCl3 |
| Calculated properties | |
|---|---|
| LogP | 11.75495 |
| Rotatable bonds | 31 |
| H bond donor | 8 |
| H bond acceptor | 9 |
| Polar surface area (PSA) | 273.97000 |
| Citations | |||||
|---|---|---|---|---|---|
| ID | Title | Year | Authors | Journal | DOI |
Synthesis of porphyrin α,ω-bis(methylamino)peptide constructs | 1999 | Matthews, Susan E.; Pouton, Colin W.; Threadgill, Michael D. | New Journal of Chemistry | ||
