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Schematic representation of peptide, linker and drug in the peptide-drug conjugates
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| RRRRRRRRG | Xanthylium, 9-[2-carboxy-6-[[(2,5-dioxo-1-pyrrolidinyl)oxy]carbonyl]phenyl]-3,6-bis(dimethylamino)-, chloride (1:1) |
| Identification | |
|---|---|
| ConjuPepDB ID | cpd01390 |
| Smiles | |
| Molecular weight | 1981.1 |
| Molecular formula | C85H138N37O19 |
| Chemical name | Peptide information |
| Sequence (one letter) | RRRRRRRRG |
| Length | 9 |
| Peptide name | N/A |
| External ID | |
|---|---|
| CAS number | 783345-28-8 |
| Other information | |
|---|---|
| Application | Chelation |
| Additional function | Promoting cellular uptake |
| Pharmacological class | other |
| Conjugate type | amide |
| Linker | no |
| Small molecule | Xanthylium, 9-[2-carboxy-6-[[(2,5-dioxo-1-pyrrolidinyl)oxy]carbonyl]phenyl]-3,6-bis(dimethylamino)-, chloride (1:1) |
| Small molecule CAS | 75929-56-5 |
| Structure method | HPLC, MALDI-TOFMS |
| Calculated properties | |
|---|---|
| LogP | -8.38241 |
| Rotatable bonds | 65 |
| H bond donor | 38 |
| H bond acceptor | 46 |
| Polar surface area (PSA) | 958.26000 |
| Citations | |||||
|---|---|---|---|---|---|
| ID | Title | Year | Authors | Journal | DOI |
Arginine carrier peptide bearing Ni(II) chelator to promote cellular uptake of histidine-tagged proteins | 2004 | Futaki, Shiroh; Niwa, Miki; Nakase, Ikuhiko; Tadokoro, Akiko; Zhang, Youjun; Nagaoka, Makoto; Wakako, Naoya; Sugiura, Yukio | Bioconjugate Chemistry | ||
