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ConjuPepDB ID: cpd00985

Chemical structure


molecule
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cpd00985


Schematic Help Icon Schematic representation of peptide, linker and drug in the peptide-drug conjugates
EEE Naproxen
Identification
ConjuPepDB ID

cpd00985

Smiles
Molecular weight

1133.39

Molecular formula

C49H63N7O24

Chemical name
Peptide information
Sequence (one letter)

EEE

Length

3

Peptide name

tripeptide

External ID
CAS number

1186099-39-7

Other information
Application

bone-targeting (prodrug)

Additional function

Inreased water solubility

Pharmacological class

Anti-inflammatory

Conjugate type

amide

Linker

no

Small molecule

Naproxen

Small molecule CAS

22204-53-1

Small molecule structure

Structure method

1H NMR, MS

NMR solvent

CDCl3 or D2O

Calculated properties
LogP

-3.24190

Rotatable bonds

38

H bond donor

15

H bond acceptor

24

Polar surface area (PSA)

511.33000

Citations
ID Title Year Authors Journal DOI

cpdart0145

Synthesis and preliminary evaluation in vitro of novel naproxen-dendritic peptide conjugates

2009

Ouyang, Liang; Zhang, Jing; Pan, Junzhu; Yan, Linna; Guo, Li

Drug Delivery

..