3D model is for representation purpose only.
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RIKPHQGQHIGQFPQIM | PEG | meso-porphyrin derivative |
Identification | |
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ConjuPepDB ID | cpd00984 |
Smiles | |
Molecular weight | 2853.45 |
Molecular formula | C146H192N34O25S |
Chemical name | Peptide information |
Sequence (one letter) | RIKPHQGQHIGQFPQIM |
Length | 17 |
Peptide name | N/A |
External ID | |
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CAS number | 1190101-28-0 |
Other information | |
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Application | Anticancer therapy, photosensitizing |
Additional function | Targeting, VEGF-R2 and tumour neovasculature |
Pharmacological class | anticancer |
Conjugate type | amide |
Linker | N/A |
Linker Type | PEG |
Small molecule | meso-porphyrin derivative |
Small molecule CAS | 1802169-94-3 |
Structure method | 1H NMR, MALDI Mass spectrometry, absorption and fluorescence spectroscopies |
Calculated properties | |
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LogP | 0.75740 |
Rotatable bonds | 52 |
H bond donor | 28 |
H bond acceptor | 33 |
Polar surface area (PSA) | 894.92000 |
Citations | |||||
---|---|---|---|---|---|
ID | Title | Year | Authors | Journal | DOI |
An efficient route to VEGF-like peptide porphyrin conjugates via microwave-assisted 'click-chemistry' | 2009 | Bakleh, M. E.; Sol, V.; Estieu-Gionnet, K.; Granet, R.; Deleris, G.; Krausz, P. | Tetrahedron |