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View Conjugates details

ConjuPepDB ID: cpd00984

Chemical structure


molecule
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cpd00984


Schematic Help Icon Schematic representation of peptide, linker and drug in the peptide-drug conjugates
RIKPHQGQHIGQFPQIM PEG meso-porphyrin derivative
Identification
ConjuPepDB ID

cpd00984

Smiles
Molecular weight

2853.45

Molecular formula

C146H192N34O25S

Chemical name
Peptide information
Sequence (one letter)

RIKPHQGQHIGQFPQIM

Length

17

Peptide name

N/A

External ID
CAS number

1190101-28-0

Other information
Application

Anticancer therapy, photosensitizing

Additional function

Targeting, VEGF-R2 and tumour neovasculature

Pharmacological class

anticancer

Conjugate type

amide

Linker

N/A

Linker Type

PEG

Small molecule

meso-porphyrin derivative

Small molecule CAS

1802169-94-3

Structure method

1H NMR, MALDI Mass spectrometry, absorption and fluorescence spectroscopies

Calculated properties
LogP

0.75740

Rotatable bonds

52

H bond donor

28

H bond acceptor

33

Polar surface area (PSA)

894.92000

Citations
ID Title Year Authors Journal DOI

cpdart0144

An efficient route to VEGF-like peptide porphyrin conjugates via microwave-assisted 'click-chemistry'

2009

Bakleh, M. E.; Sol, V.; Estieu-Gionnet, K.; Granet, R.; Deleris, G.; Krausz, P.

Tetrahedron

..