conjupepdb_log

View Conjugates details

ConjuPepDB ID: cpd00230

Chemical structure


molecule
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cpd00230


Schematic Help Icon Schematic representation of peptide, linker and drug in the peptide-drug conjugates
FCFWWKTFG butyramide N-[2-[(4-hydroxyphenyl)amino]-3-pyridinyl]-4-methoxy-Benzenesulfonamide
Identification
ConjuPepDB ID

cpd00230

Smiles
Inchi Key

InChIKey=SPFFQJMMWRKKEL-QGNYYCEWSA-N

Molecular weight

1759.68

Molecular formula

C89H101N17O16S3

Chemical name
Peptide information
Sequence (one letter)

FCFWWKTFG

Length

9

Peptide name

somatostatin backbone cyclic analog

External ID
CAS number

1841405-75-1

Other information
Application

Anticancer therapy

Additional function

Targeting somatostatin expressing cells

Pharmacological class

anticancer

Conjugate type

amide

Linker

N/A

Linker Type

butyramide

Small molecule

N-[2-[(4-hydroxyphenyl)amino]-3-pyridinyl]-4-methoxy-Benzenesulfonamide

Small molecule CAS

141430-65-1

Small molecule structure

Calculated properties
LogP

3.61363

Rotatable bonds

31

H bond donor

16

H bond acceptor

18

Polar surface area (PSA)

492.68000

Citations
ID Title Year Authors Journal DOI

Cpdart0051

Synthesis, drug release, and biological evaluation of new anticancer drug-bioconjugates containing somatostatin backbone cyclic analog as a targeting moiety

2015

Redko, Boris; Ragozin, Elena; Andreii, Bazylevich; Helena, Tuchinsky; Amnon, Albeck; Talia, Shekhter Zahavi; Mor, Oron-Herman; Genady, Kostenich; Gary, Gellerman

Biopolymers

..