3D model is for representation purpose only.
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NFGAILSS | 4-(Chlorocarbonyl)-1,2-benzenedicarboxylic acid |
Identification | |
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ConjuPepDB ID | cpd00146 |
Smiles | |
Inchi Key | InChIKey=HHGLCMZRMLZOSC-CBTREZALSA-N |
Molecular weight | 999.419 |
Molecular formula | C45H61N9O17 |
Chemical name | Peptide information |
Sequence (one letter) | NFGAILSS |
Length | 8 |
Peptide name | amyloid disrupting peptide |
External ID | |
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CAS number | 2130904-39-9 |
Other information | |
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Application | Type 2 diabetes therapy, amylin aggregation inhibition |
Additional function | Self-assembly |
Pharmacological class | neurological |
Conjugate type | amide |
Linker | no |
Small molecule | 4-(Chlorocarbonyl)-1,2-benzenedicarboxylic acid |
Small molecule CAS | 53659-79-3 |
Small molecule structure | |
Calculated properties | |
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LogP | -3.21500 |
Rotatable bonds | 29 |
H bond donor | 14 |
H bond acceptor | 17 |
Polar surface area (PSA) | 428.25000 |
Citations | |||||
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ID | Title | Year | Authors | Journal | DOI |
Peptide Conjugates of Benzene Carboxylic Acids as Agonists and Antagonists of Amylin Aggregation | 2017 | Profit, Adam A.; Vedad, Jayson; Desamero, Ruel Z. B. | Bioconjugate Chemistry |