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ConjuPepDB ID: cpd00075

Chemical structure


molecule
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cpd00075


Schematic Help Icon Schematic representation of peptide, linker and drug in the peptide-drug conjugates
PHWSY (R)-5-oxo-2-pyrrolidinecarboxamide
Identification
ConjuPepDB ID

cpd00075

Smiles
Inchi Key

InChIKey=YZFKREISKFLOJV-ZTTXAYQISA-N

Molecular weight

816.344

Molecular formula

C40H48N8O11

Chemical name
Peptide information
Sequence (one letter)

PHWSY

Length

5

Peptide name

pentapeptide, linear

External ID
CAS number

2230864-93-2

Other information
Application

Synthesis, tryptophan chemoselective beta?position conjugation

Additional function

Possible appications as protein labeling and various bioconjugations

Pharmacological class

other

Conjugate type

amide

Linker

no

Small molecule

(R)-5-oxo-2-pyrrolidinecarboxamide

Small molecule CAS

118929-65-0

Small molecule structure

Structure method

NMR

Calculated properties
LogP

-0.81986

Rotatable bonds

22

H bond donor

8

H bond acceptor

10

Polar surface area (PSA)

272.17000

Citations
ID Title Year Authors Journal DOI

Cpdart0031

Chemoselective Peptide Modification via Photocatalytic Tryptophan β-Position Conjugation

2018

Yu, Younong; Zhang, Li-Kang; Buevich, Alexei V.; Li, Guoqing; Tang, Haiqun; Vachal, Petr; Colletti, Steven L.; Shi, Zhi-Cai

Journal of the American Chemical Society

..