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Schematic representation of peptide, linker and drug in the peptide-drug conjugates
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|---|---|---|---|---|
| ARHTDYK | Pyridoxine |
| Identification | |
|---|---|
| ConjuPepDB ID | cpd01636 |
| Smiles | |
| Molecular weight | 1040.5 |
| Molecular formula | C46H68N14O14 |
| Chemical name | Peptide information |
| Sequence (one letter) | ARHTDYK |
| Length | 7 |
| Peptide name | N/A |
| External ID | |
|---|---|
| CAS number | 160056-10-0 |
| Other information | |
|---|---|
| Application | Synthesis |
| Additional function | Studying the cellular uptake, intracellular localization and metabolism of such conjugates |
| Pharmacological class | other |
| Conjugate type | amine |
| Linker | no |
| Small molecule | Pyridoxine |
| Small molecule CAS | 65-23-6 |
| Small molecule structure | |
| Structure method | 1H-NMR, HPLC |
| NMR solvent | CD3OD |
| Calculated properties | |
|---|---|
| LogP | -9.80072 |
| Rotatable bonds | 32 |
| H bond donor | 18 |
| H bond acceptor | 21 |
| Polar surface area (PSA) | 471.64000 |
| Citations | |||||
|---|---|---|---|---|---|
| ID | Title | Year | Authors | Journal | DOI |
Preparation of Vitamin B6-Conjugated Peptides at the Amino Terminus and of Vitamin B6-Peptide-Oligonucleotide Conjugates | 1994 | Zhu, Tianmin; Stein, Stanley | Bioconjugate Chemistry | ||
