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Schematic representation of peptide, linker and drug in the peptide-drug conjugates
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|---|---|---|---|---|
| GGGI | 4-Carboxybenzenesulfonamide |
| Identification | |
|---|---|
| ConjuPepDB ID | cpd01595 |
| Smiles | |
| Molecular weight | 485.158 |
| Molecular formula | C19H27N5O8S |
| Chemical name | Peptide information |
| Sequence (one letter) | GGGI |
| Length | 4 |
| Peptide name | tetrapeptide |
| External ID | |
|---|---|
| CAS number | 176171-13-4 |
| Other information | |
|---|---|
| Application | Synthesis |
| Additional function | Using conjugates as probes for secondary binding sites in carbonic anhydrase |
| Pharmacological class | other |
| Conjugate type | amide |
| Linker | no |
| Small molecule | 4-Carboxybenzenesulfonamide |
| Small molecule CAS | 138-41-0 |
| Small molecule structure | |
| Structure method | NMR and HMRS |
| Calculated properties | |
|---|---|
| LogP | -2.28345 |
| Rotatable bonds | 12 |
| H bond donor | 6 |
| H bond acceptor | 8 |
| Polar surface area (PSA) | 213.86000 |
| Citations | |||||
|---|---|---|---|---|---|
| ID | Title | Year | Authors | Journal | DOI |
Benzenesulfonamide-peptide conjugates as probes for secondary binding sites near the active site of carbonic anhydrase | 1996 | Sigal, George B.; Whitesides, George M. | Bioorganic & Medicinal Chemistry Letters | ||
