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Schematic representation of peptide, linker and drug in the peptide-drug conjugates
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|---|---|---|---|---|
| GGGG | propyl | Camptothecin |
| Identification | |
|---|---|
| ConjuPepDB ID | cpd01536 |
| Smiles | |
| Molecular weight | 649.25 |
| Molecular formula | C31H35N7O9 |
| Chemical name | Peptide information |
| Sequence (one letter) | GGGG |
| Length | 4 |
| Peptide name | oligoglycin |
| External ID | |
|---|---|
| CAS number | 330808-06-5 |
| Other information | |
|---|---|
| Application | Synthesis |
| Pharmacological class | anticancer |
| Conjugate type | amide |
| Linker | N/A |
| Linker Type | propyl |
| Small molecule | Camptothecin |
| Small molecule CAS | 7689-03-04 |
| Calculated properties | |
|---|---|
| LogP | -4.09559 |
| Rotatable bonds | 13 |
| H bond donor | 6 |
| H bond acceptor | 10 |
| Polar surface area (PSA) | 231.38000 |
| Citations | |||||
|---|---|---|---|---|---|
| ID | Title | Year | Authors | Journal | DOI |
Determinants for the drug release from T-0128, camptothecin analog-carboxymethyl dextran conjugate | 2000 | Harada, M.; Sakakibara, H.; Yano, T.; Suzuki, T.; Okuno, S. | Journal of Controlled Release | ||
