3D model is for representation purpose only.
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ANKASYQSSSL | Doxorubicin |
Identification | |
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ConjuPepDB ID | cpd01523 |
Smiles | |
Molecular weight | 1721.73 |
Molecular formula | C77H107N15O30 |
Chemical name | Peptide information |
Sequence (one letter) | ANKASYQSSSL |
Length | 11 |
Peptide name | N/A |
External ID | |
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CAS number | 174640-88-1 |
Other information | |
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Application | Anticancer therapy |
Additional function | Targeting, prostate cancer |
Pharmacological class | anticancer |
Conjugate type | amide |
Linker | no |
Small molecule | Doxorubicin |
Small molecule CAS | 23214-92-9 |
Structure method | RP-HPLC, FT/ICR/MS with ES |
Calculated properties | |
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LogP | -9.95786 |
Rotatable bonds | 45 |
H bond donor | 25 |
H bond acceptor | 31 |
Polar surface area (PSA) | 742.60000 |
Citations | |||||
---|---|---|---|---|---|
ID | Title | Year | Authors | Journal | DOI |
The Synthesis of a Prodrug of Doxorubicin Designed to Provide Reduced Systemic Toxicity and Greater Target Efficacy | 2001 | Garsky, Victor M.; Lumma, Patricia K.; Feng, Dong-Mei; Wai, Jenny; Ramjit, Harri G.; Sardana, Mohinder K.; Oliff, Allen; Jones, Raymond E.; DeFeo-Jones, Deborah; Freidinger, Roger M. | Journal of Medicinal Chemistry |