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View Conjugates details

ConjuPepDB ID: cpd01517

Chemical structure


molecule
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cpd01517


Schematic Help Icon Schematic representation of peptide, linker and drug in the peptide-drug conjugates
XASXQSL Doxorubicin
Identification
ConjuPepDB ID

cpd01517

Smiles
Molecular weight

1381.58

Molecular formula

C64H87N9O25

Chemical name
Peptide information
Sequence (one letter)

XASXQSL

Length

7

Peptide name

N/A

External ID
CAS number

207396-04-1

Other information
Application

Anticancer therapy

Additional function

Targeting, prostate cancer

Pharmacological class

anticancer

Conjugate type

amide

Linker

no

Small molecule

Doxorubicin

Small molecule CAS

23214-92-8

Structure method

RP-HPLC, FT/ICR/MS with ES

Calculated properties
LogP

-3.72511

Rotatable bonds

30

H bond donor

17

H bond acceptor

25

Polar surface area (PSA)

545.14000

Citations
ID Title Year Authors Journal DOI

cpdart0235

The Synthesis of a Prodrug of Doxorubicin Designed to Provide Reduced Systemic Toxicity and Greater Target Efficacy

2001

Garsky, Victor M.; Lumma, Patricia K.; Feng, Dong-Mei; Wai, Jenny; Ramjit, Harri G.; Sardana, Mohinder K.; Oliff, Allen; Jones, Raymond E.; DeFeo-Jones, Deborah; Freidinger, Roger M.

Journal of Medicinal Chemistry

..