conjupepdb_log

View Conjugates details

ConjuPepDB ID: cpd01451

Chemical structure


molecule
3D viewer Help Icon Use the buttons at the bottom of Jsmol viewer to see different representations, ON/OFF Hydrogens, and ON/OFF rotation.

3D model is for representation purpose only.

cpd01451


Schematic Help Icon Schematic representation of peptide, linker and drug in the peptide-drug conjugates
GSXYSCFWKTCT Camptothecin
Identification
ConjuPepDB ID

cpd01451

Smiles
Molecular weight

1809.72

Molecular formula

C86H107N17O23S2

Chemical name
Peptide information
Sequence (one letter)

GSXYSCFWKTCT

Length

12

Peptide name

N/A

External ID
CAS number

566181-74-6

Other information
Application

Anticancer therapy and tumor imaging, radioisotope internalization

Additional function

Somatostatin receptor targeting

Pharmacological class

anticancer

Conjugate type

carbamate

Linker

no

Small molecule

Camptothecin

Small molecule CAS

7689-03-04

Structure method

HPLC

Calculated properties
LogP

-4.53346

Rotatable bonds

36

H bond donor

20

H bond acceptor

23

Polar surface area (PSA)

615.42000

Citations
ID Title Year Authors Journal DOI

cpdart0224

An adjustable release rate linking strategy for cytotoxin-Peptide conjugates

2003

Fuselier, Joseph A.; Sun, Lichun; Woltering, S. Nathaniel; Murphy, William A.; Vasilevich, Natalya; Coy, David H.

Bioorganic & Medicinal Chemistry Letters

..