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View Conjugates details

ConjuPepDB ID: cpd01448

Chemical structure


molecule
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cpd01448


Schematic Help Icon Schematic representation of peptide, linker and drug in the peptide-drug conjugates
XRXXXXXR hexanamide 9-Acridinecarboxylic acid
Identification
ConjuPepDB ID

cpd01448

Smiles
Molecular weight

1514.6

Molecular formula

C69H78N24O17

Chemical name
Peptide information
Sequence (one letter)

XRXXXXXR

Length

8

Peptide name

unnatural heptapeptide

External ID
CAS number

560071-08-1

Other information
Application

Synthesis

Additional function

Interacalators and DNA binding

Pharmacological class

other

Conjugate type

amide

Linker

N/A

Linker Type

hexanamide

Small molecule

9-Acridinecarboxylic acid

Small molecule CAS

5336-90-3

Small molecule 2

acid binding block?

Structure method

HPLC

Calculated properties
LogP

-6.64338

Rotatable bonds

34

H bond donor

18

H bond acceptor

24

Polar surface area (PSA)

601.43000

Citations
ID Title Year Authors Journal DOI

cpdart0223

New dsDNA-binding hybrid molecules combining an unnatural peptide and an intercalating moiety

2003

Chaltin, Patrick; Borgions, Filip; Rozenski, Jef; Van Aerschot, Arthur; Herdewijn, Piet

Helvetica Chimica Acta

..