conjupepdb_log

View Conjugates details

ConjuPepDB ID: cpd01428

Chemical structure


molecule
3D viewer Help Icon Use the buttons at the bottom of Jsmol viewer to see different representations, ON/OFF Hydrogens, and ON/OFF rotation.

3D model is for representation purpose only.

cpd01428


Schematic Help Icon Schematic representation of peptide, linker and drug in the peptide-drug conjugates
XRXXXXXR hexanamide Fluorenone-2-carboxylic acid
Identification
ConjuPepDB ID

cpd01428

Smiles
Molecular weight

1529.6

Molecular formula

C70H79N23O18

Chemical name
Peptide information
Sequence (one letter)

XRXXXXXR

Length

8

Peptide name

unnatural heptapeptide

External ID
CAS number

560071-35-4

Other information
Application

Synthesis

Additional function

Interacalators and DNA binding

Pharmacological class

other

Conjugate type

amide

Linker

N/A

Linker Type

hexanamide

Small molecule

Fluorenone-2-carboxylic acid

Small molecule CAS

784-50-9

Small molecule 2

acid binding block?

Structure method

HPLC

Calculated properties
LogP

-6.78439

Rotatable bonds

35

H bond donor

18

H bond acceptor

24

Polar surface area (PSA)

605.61000

Citations
ID Title Year Authors Journal DOI

cpdart0223

New dsDNA-binding hybrid molecules combining an unnatural peptide and an intercalating moiety

2003

Chaltin, Patrick; Borgions, Filip; Rozenski, Jef; Van Aerschot, Arthur; Herdewijn, Piet

Helvetica Chimica Acta

..