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Schematic representation of peptide, linker and drug in the peptide-drug conjugates
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|---|---|---|---|---|
| XASXQSL | Doxorubicin |
| Identification | |
|---|---|
| ConjuPepDB ID | cpd01426 |
| Smiles | |
| Molecular weight | 1573.68 |
| Molecular formula | C79H99N9O25 |
| Chemical name | Peptide information |
| Sequence (one letter) | XASXQSL |
| Length | 7 |
| Peptide name | N/A |
| External ID | |
|---|---|
| CAS number | 207395-90-2 |
| Other information | |
|---|---|
| Application | Synthesis |
| Pharmacological class | anticancer |
| Conjugate type | amide |
| Linker | no |
| Small molecule | Doxorubicin |
| Small molecule CAS | 23214-92-8 |
| Structure method | 1H and 13C NMR |
| NMR solvent | DMF-d7 |
| Calculated properties | |
|---|---|
| LogP | 0.05124 |
| Rotatable bonds | 34 |
| H bond donor | 16 |
| H bond acceptor | 24 |
| Polar surface area (PSA) | 534.14000 |
| Citations | |||||
|---|---|---|---|---|---|
| ID | Title | Year | Authors | Journal | DOI |
An efficient synthesis of a doxorubicin-peptide conjugate | 2003 | Shi, Yao-Jun; Cameron, Mark; Dolling, Ulf H.; Lieberman, David R.; Lynch, Joseph E.; Reamer, Robert A.; Robbins, Michael A.; Volante, R. P.; Reider, Paul J. | Synlett | ||
