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Schematic representation of peptide, linker and drug in the peptide-drug conjugates
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| XKKL | 3,5,6,7-tetrahydro-6-octyl-1,3,5,7-tetraoxo-benzo[1,2-c:4,5-c′]dipyrrole-2(1H)-acetic acid |
| Identification | |
|---|---|
| ConjuPepDB ID | cpd01415 |
| Smiles | |
| Inchi Key | InChIKey=NVSYXOOBOBFFAU-UHFFFAOYSA-N |
| Molecular weight | 1365.75 |
| Molecular formula | C77H103N7O15 |
| Chemical name | Peptide information |
| Sequence (one letter) | XKKL |
| Length | 4 |
| Peptide name | tetrapeptide |
| External ID | |
|---|---|
| CAS number | 656248-86-1 |
| Other information | |
|---|---|
| Application | Synthesis |
| Additional function | Selfassembly |
| Pharmacological class | other |
| Conjugate type | amide |
| Linker | no |
| Small molecule | 3,5,6,7-tetrahydro-6-octyl-1,3,5,7-tetraoxo-benzo[1,2-c:4,5-c′]dipyrrole-2(1H)-acetic acid |
| Small molecule CAS | 656248-75-8 |
| Structure method | 1H NMR, HPLC |
| NMR solvent | DMSO-d6 |
| Calculated properties | |
|---|---|
| LogP | 11.61808 |
| Rotatable bonds | 48 |
| H bond donor | 5 |
| H bond acceptor | 14 |
| Polar surface area (PSA) | 283.48000 |
| Citations | |||||
|---|---|---|---|---|---|
| ID | Title | Year | Authors | Journal | DOI |
Zipper-Featured δ-Peptide Foldamers Driven by Donor-Acceptor Interaction. Design, Synthesis, and Characterization | 2004 | Zhao, Xin; Jia, Mu-Xin; Jiang, Xi-Kui; Wu, Li-Zhu; Li, Zhan-Ting; Chen, Guang-Ju | Journal of Organic Chemistry | ||
