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Schematic representation of peptide, linker and drug in the peptide-drug conjugates
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|---|---|---|---|---|
| XXXXXXXXG | Nitrilotriacetic acid |
| Identification | |
|---|---|
| ConjuPepDB ID | cpd01392 |
| Smiles | |
| Inchi Key | InChIKey=GSHGCFXBJJIRHL-UHFFFAOYSA-N |
| Molecular weight | 3626.61 |
| Molecular formula | C166H247N35O40S8 |
| Chemical name | Peptide information |
| Sequence (one letter) | XXXXXXXXG |
| Length | 9 |
| Peptide name | N/A |
| External ID | |
|---|---|
| CAS number | 721397-19-9 |
| Other information | |
|---|---|
| Application | Chelation |
| Additional function | Promoting cellular uptake |
| Pharmacological class | other |
| Conjugate type | amide |
| Linker | no |
| Small molecule | Nitrilotriacetic acid |
| Small molecule CAS | 139-13-9 |
| Structure method | HPLC, MALDI-TOFMS |
| Calculated properties | |
|---|---|
| LogP | 10.13631 |
| Rotatable bonds | 69 |
| H bond donor | 37 |
| H bond acceptor | 57 |
| Polar surface area (PSA) | 1136.38000 |
| Citations | |||||
|---|---|---|---|---|---|
| ID | Title | Year | Authors | Journal | DOI |
Arginine carrier peptide bearing Ni(II) chelator to promote cellular uptake of histidine-tagged proteins | 2004 | Futaki, Shiroh; Niwa, Miki; Nakase, Ikuhiko; Tadokoro, Akiko; Zhang, Youjun; Nagaoka, Makoto; Wakako, Naoya; Sugiura, Yukio | Bioconjugate Chemistry | ||
