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Schematic representation of peptide, linker and drug in the peptide-drug conjugates
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| QRPAK | 1H-Imidazol-1-yloxy, 2-[4-(2-ethoxy-2-oxoethoxy)phenyl]-4,5-dihydro-4,4,5,5-tetramethyl-, 3-oxide |
| Identification | |
|---|---|
| ConjuPepDB ID | cpd01320 |
| Smiles | |
| Molecular weight | 887.474 |
| Molecular formula | C40H63N12O11 |
| Chemical name | Peptide information |
| Sequence (one letter) | QRPAK |
| Length | 5 |
| Peptide name | N/A |
| External ID | |
|---|---|
| CAS number | 860020-58-2 |
| Other information | |
|---|---|
| Application | Antithrombotic |
| Additional function | Free radical scavenging |
| Pharmacological class | other |
| Conjugate type | amide |
| Linker | no |
| Small molecule | 1H-Imidazol-1-yloxy, 2-[4-(2-ethoxy-2-oxoethoxy)phenyl]-4,5-dihydro-4,4,5,5-tetramethyl-, 3-oxide |
| Small molecule CAS | 642097-77-6 |
| Structure method | 1H NMR, HPLC |
| NMR solvent | DMSO |
| Calculated properties | |
|---|---|
| LogP | -4.86658 |
| Rotatable bonds | 24 |
| H bond donor | 10 |
| H bond acceptor | 17 |
| Polar surface area (PSA) | 346.24000 |
| Citations | |||||
|---|---|---|---|---|---|
| ID | Title | Year | Authors | Journal | DOI |
Synthesis and Biological Activity of Nitronyl Nitroxide Containing Peptides | 2005 | Zhao, Ming; Liu, Junling; Wang, Chao; Wang, Lili; Liu, Hu; Peng, Shiqi | Journal of Medicinal Chemistry | ||
