Use the buttons at the bottom of Jsmol viewer to see different representations, ON/OFF Hydrogens, and ON/OFF rotation.
3D model is for representation purpose only.
.
.
Schematic representation of peptide, linker and drug in the peptide-drug conjugates
 |
 |
 |
|
 |
|---|---|---|---|---|
| GPKKKRKV | PEG | Porphine derivative |
| Identification | |
|---|---|
| ConjuPepDB ID | cpd01303 |
| Smiles | |
| Molecular weight | 1987.09 |
| Molecular formula | C104H142N22O18 |
| Chemical name | Peptide information |
| Sequence (one letter) | GPKKKRKV |
| Length | 8 |
| Peptide name | N/A |
| External ID | |
|---|---|
| CAS number | 880760-12-3 |
| Other information | |
|---|---|
| Application | Anticancer therapy, photosensitizer |
| Additional function | Improving solubility an cell penetration |
| Pharmacological class | anticancer |
| Conjugate type | amide |
| Linker | N/A |
| Linker Type | PEG |
| Small molecule | Porphine derivative |
| Small molecule CAS | 67605-64-5 |
| Structure method | 1H NMR, HPLC |
| NMR solvent | D2O |
| Calculated properties | |
|---|---|
| LogP | 2.42988 |
| Rotatable bonds | 65 |
| H bond donor | 19 |
| H bond acceptor | 27 |
| Polar surface area (PSA) | 613.25000 |
| Citations | |||||
|---|---|---|---|---|---|
| ID | Title | Year | Authors | Journal | DOI |
Peptide-Mediated Cell Transport of Water Soluble Porphyrin Conjugates | 2006 | Sibrian-Vazquez, Martha; Jensen, Timothy J.; Hammer, Robert P.; Vicente, M. Graca H. | Journal of Medicinal Chemistry | ||
