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View Conjugates details

ConjuPepDB ID: cpd01291

Chemical structure


molecule
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cpd01291


Schematic Help Icon Schematic representation of peptide, linker and drug in the peptide-drug conjugates
GPLG Doxorubicin
Identification
ConjuPepDB ID

cpd01291

Smiles
Molecular weight

867.354

Molecular formula

C42H53N5O15

Chemical name
Peptide information
Sequence (one letter)

GPLG

Length

4

Peptide name

N/A

External ID
CAS number

916686-24-3

Other information
Application

Anticancer therapy

Additional function

Targeting, matrix metalloproteinases (MMPs) expressed from tumors

Pharmacological class

anticancer

Conjugate type

amide

Linker

no

Small molecule

Doxorubicin

Small molecule CAS

23214-92-8

Structure method

HPLC

Calculated properties
LogP

-0.72990

Rotatable bonds

14

H bond donor

9

H bond acceptor

16

Polar surface area (PSA)

313.68000

Citations
ID Title Year Authors Journal DOI

cpdart0196

Peptide-doxorubicin conjugates specifically degraded by matrix metalloproteinases expressed from tumor

2006

Lee, Gee Young; Song, Ji-hye; Kim, Sang Yoon; Park, Kyeongsoon; Byun, Youngro

Drug Development Research

..