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ConjuPepDB ID: cpd01284

Chemical structure


molecule
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cpd01284


Schematic Help Icon Schematic representation of peptide, linker and drug in the peptide-drug conjugates
EGFLGC Methotrexate
Identification
ConjuPepDB ID

cpd01284

Smiles
Molecular weight

930.392

Molecular formula

C42H54N14O9S

Chemical name
Peptide information
Sequence (one letter)

EGFLGC

Length

6

Peptide name

N/A

External ID
CAS number

900179-59-1

Other information
Application

Anticancer therapy

Additional function

Targeting, chemotactic

Pharmacological class

anticancer

Conjugate type

amide

Linker

no

Small molecule

Methotrexate

Small molecule CAS

59-05-2

Structure method

RP-HPLC

Calculated properties
LogP

-1.67021

Rotatable bonds

24

H bond donor

11

H bond acceptor

16

Polar surface area (PSA)

361.83000

Citations
ID Title Year Authors Journal DOI

cpdart0195

Synthesis of oligotuftsin-based branched oligopeptide conjugates for chemotactic drug targeting

2006

Mezo, Gabor; Lang, Orsolya; Jakab, Annamaria; Bai, Katalin B.; Szabo, Ildiko; Schlosser, Gitta; Lang, Julianna; Kohidai, Laszlo; Hudecz, Ferenc

Journal of Peptide Science

..