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Schematic representation of peptide, linker and drug in the peptide-drug conjugates
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|---|---|---|---|---|
| GWS | DOTA |
| Identification | |
|---|---|
| ConjuPepDB ID | cpd01281 |
| Smiles | |
| Inchi Key | InChIKey=WLWWMDRPXPFYQL-UHFFFAOYSA-N |
| Molecular weight | 756.284 |
| Molecular formula | C30H45N8O13P |
| Chemical name | Peptide information |
| Sequence (one letter) | GWS |
| Length | 3 |
| Peptide name | N/A |
| External ID | |
|---|---|
| CAS number | 899838-95-0 |
| Other information | |
|---|---|
| Application | Diagnosis, luminescence switch reports enzymatic dephosphorilation |
| Pharmacological class | other |
| Conjugate type | amide |
| Linker | no |
| Small molecule | DOTA |
| Small molecule CAS | 60239-18-1 |
| Calculated properties | |
|---|---|
| LogP | -5.47272 |
| Rotatable bonds | 17 |
| H bond donor | 9 |
| H bond acceptor | 16 |
| Polar surface area (PSA) | 308.70000 |
| Citations | |||||
|---|---|---|---|---|---|
| ID | Title | Year | Authors | Journal | DOI |
Phosphorylation State-Responsive Lanthanide Peptide Conjugates: A Luminescence Switch Based on Reversible Complex Reorganization | 2006 | Tremblay, Matthew S.; Zhu, Qing; Marti, Angel A.; Dyer, Joanne; Halim, Marlin; Jockusch, Steffen; Turro, Nicholas J.; Sames, Dalibor | Organic Letters | ||
