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Schematic representation of peptide, linker and drug in the peptide-drug conjugates
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 |
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|---|---|---|---|---|
| XYQWAVGHLM | succinic acid | Paclitaxel |
| Identification | |
|---|---|
| ConjuPepDB ID | cpd01279 |
| Smiles | |
| Molecular weight | 2166.92 |
| Molecular formula | C108H134N16O30S |
| Chemical name | Peptide information |
| Sequence (one letter) | XYQWAVGHLM |
| Length | 10 |
| Peptide name | N/A |
| External ID | |
|---|---|
| CAS number | 888974-90-1 |
| Other information | |
|---|---|
| Application | Antitumor therapy |
| Additional function | tumor-specific drug delivery |
| Pharmacological class | anticancer |
| Conjugate type | amide |
| Linker | N/A |
| Linker Type | succinic acid |
| Small molecule | Paclitaxel |
| Small molecule CAS | 33069-62-4 |
| Structure method | RP-HPLC |
| Calculated properties | |
|---|---|
| LogP | -0.13784 |
| Rotatable bonds | 57 |
| H bond donor | 19 |
| H bond acceptor | 26 |
| Polar surface area (PSA) | 706.54000 |
| Citations | |||||
|---|---|---|---|---|---|
| ID | Title | Year | Authors | Journal | DOI |
Single-Drug Multiligand Conjugates: Synthesis and Preliminary Cytotoxicity Evaluation of a Paclitaxel-Dipeptide "Scorpion"" Molecule" | 2006 | Safavy, Ahmad; Raisch, Kevin P.; Matusiak, Damien; Bhatnagar, Saloni; Helson, Lawrence | Bioconjugate Chemistry | ||
