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View Conjugates details

ConjuPepDB ID: cpd01279

Chemical structure


molecule
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cpd01279


Schematic Help Icon Schematic representation of peptide, linker and drug in the peptide-drug conjugates
XYQWAVGHLM succinic acid Paclitaxel
Identification
ConjuPepDB ID

cpd01279

Smiles
Molecular weight

2166.92

Molecular formula

C108H134N16O30S

Chemical name
Peptide information
Sequence (one letter)

XYQWAVGHLM

Length

10

Peptide name

N/A

External ID
CAS number

888974-90-1

Other information
Application

Antitumor therapy

Additional function

tumor-specific drug delivery

Pharmacological class

anticancer

Conjugate type

amide

Linker

N/A

Linker Type

succinic acid

Small molecule

Paclitaxel

Small molecule CAS

33069-62-4

Structure method

RP-HPLC

Calculated properties
LogP

-0.13784

Rotatable bonds

57

H bond donor

19

H bond acceptor

26

Polar surface area (PSA)

706.54000

Citations
ID Title Year Authors Journal DOI

cpdart0193

Single-Drug Multiligand Conjugates: Synthesis and Preliminary Cytotoxicity Evaluation of a Paclitaxel-Dipeptide "Scorpion"" Molecule"

2006

Safavy, Ahmad; Raisch, Kevin P.; Matusiak, Damien; Bhatnagar, Saloni; Helson, Lawrence

Bioconjugate Chemistry

..