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Schematic representation of peptide, linker and drug in the peptide-drug conjugates
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|---|---|---|---|---|
| CGGRKKRRQRRR | mercaptoacetic acid | Adenosine monophosphate |
| Identification | |
|---|---|
| ConjuPepDB ID | cpd01244 |
| Smiles | |
| Molecular weight | 2031.05 |
| Molecular formula | C79H139N40O20PS |
| Chemical name | Peptide information |
| Sequence (one letter) | CGGRKKRRQRRR |
| Length | 12 |
| Peptide name | N/A |
| External ID | |
|---|---|
| CAS number | 917877-31-7 |
| Other information | |
|---|---|
| Application | Antimicrobial, antiviral (HIV) |
| Additional function | peptide label with fluoresceine |
| Pharmacological class | abtimicrobial, antiviral |
| Conjugate type | sulfide |
| Linker | N/A |
| Linker Type | mercaptoacetic acid |
| Small molecule | Adenosine monophosphate |
| Small molecule CAS | 61-19-8 |
| Structure method | 1H NMR |
| NMR solvent | CDCl3 |
| Calculated properties | |
|---|---|
| LogP | -15.99826 |
| Rotatable bonds | 69 |
| H bond donor | 38 |
| H bond acceptor | 45 |
| Polar surface area (PSA) | 1027.90000 |
| Citations | |||||
|---|---|---|---|---|---|
| ID | Title | Year | Authors | Journal | DOI |
Delivery of 2-5A cargo into living cells using the Tat cell penetrating peptide: 2-5A-tat | 2006 | Zhou, Longhu; Thakur, Chandar S.; Molinaro, Ross J.; Paranjape, Jayashree M.; Hoppes, Rieuwert; Jeang, Kuan-Teh; Silverman, Robert H.; Torrence, Paul F. | Bioorganic & Medicinal Chemistry | ||
