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Schematic representation of peptide, linker and drug in the peptide-drug conjugates
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|---|---|---|---|---|
| NFP | Azidothymidine |
| Identification | |
|---|---|
| ConjuPepDB ID | cpd01200 |
| Smiles | |
| Molecular weight | 625.261 |
| Molecular formula | C28H35N9O8 |
| Chemical name | Peptide information |
| Sequence (one letter) | NFP |
| Length | 3 |
| Peptide name | tripeptide |
| External ID | |
|---|---|
| CAS number | 1029940-42-8 |
| Other information | |
|---|---|
| Application | Antibiotic, antiviral (HIV) |
| Additional function | Targeting HIV-infected cells |
| Pharmacological class | antimicrobial, antiviral |
| Conjugate type | ester |
| Linker | no |
| Small molecule | Azidothymidine |
| Small molecule CAS | 30516-87-1 |
| Structure method | 1H-NMR, HPLC, ESI-MS |
| NMR solvent | CDCl3 |
| Calculated properties | |
|---|---|
| LogP | -0.51595 |
| Rotatable bonds | 13 |
| H bond donor | 4 |
| H bond acceptor | 10 |
| Polar surface area (PSA) | 240.84000 |
| Citations | |||||
|---|---|---|---|---|---|
| ID | Title | Year | Authors | Journal | DOI |
AZT and AZT-monophosphate prodrugs incorporating HIV-protease substrate fragment: synthesis and evaluation as specific drug delivery systems | 2006 | Liotard, Jean-Francois; Mehiri, Mohamed; Di Giorgio, Audrey; Boggetto, Nicole; Reboud-Ravaux, Michele; Aubertin, Anne-Marie; Condom, Roger; Patino, Nadia | Antiviral Chemistry & Chemotherapy | ||
