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Schematic representation of peptide, linker and drug in the peptide-drug conjugates
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| DXAXG | 2,3-Dihydro-2,2,4,6,7-pentamethyl-5-benzofuransulfonic acid |
| Identification | |
|---|---|
| ConjuPepDB ID | cpd01194 |
| Smiles | |
| Molecular weight | 1015.5 |
| Molecular formula | C48H73N9O13S |
| Chemical name | Peptide information |
| Sequence (one letter) | DXAXG |
| Length | 5 |
| Peptide name | N/A |
| External ID | |
|---|---|
| CAS number | 1007310-23-7 |
| Other information | |
|---|---|
| Application | Anticancer therapy, cell adhesion |
| Additional function | Targeting integrin |
| Pharmacological class | anticancer |
| Conjugate type | sulfonamide |
| Linker | no |
| Small molecule | 2,3-Dihydro-2,2,4,6,7-pentamethyl-5-benzofuransulfonic acid |
| Small molecule CAS | 1430820-46-4 |
| Structure method | 1H-NMR, HPLC |
| NMR solvent | CDCl3 |
| Calculated properties | |
|---|---|
| LogP | 0.39546 |
| Rotatable bonds | 25 |
| H bond donor | 10 |
| H bond acceptor | 14 |
| Polar surface area (PSA) | 335.63000 |
| Citations | |||||
|---|---|---|---|---|---|
| ID | Title | Year | Authors | Journal | DOI |
Bifunctional ligands that target cells displaying the αvβ3 integrin | 2007 | Owen, Robert M.; Carlson, Coby B.; Xu, Jinwang; Mowery, Patricia; Fasella, Elisabetta; Kiessling, Laura L. | ChemBioChem | ||
