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Schematic representation of peptide, linker and drug in the peptide-drug conjugates
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| ARGDX | PEG | O-β-D-Galactopyranosyl-(1→3)-O-β-D-galactopyranosyl-(1→4)-β-D-glucopyranose |
| Identification | |
|---|---|
| ConjuPepDB ID | cpd01192 |
| Smiles | |
| Molecular weight | 1346.56 |
| Molecular formula | C56H86N10O28 |
| Chemical name | Peptide information |
| Sequence (one letter) | ARGDX |
| Length | 5 |
| Peptide name | N/A |
| External ID | |
|---|---|
| CAS number | 1007310-50-0 |
| Other information | |
|---|---|
| Application | Anticancer therapy, cell adhesion |
| Additional function | Targeting integrin |
| Pharmacological class | anticancer |
| Linker | N/A |
| Linker Type | PEG |
| Small molecule | O-β-D-Galactopyranosyl-(1→3)-O-β-D-galactopyranosyl-(1→4)-β-D-glucopyranose |
| Small molecule CAS | 273932-91-5 |
| Structure method | 1H-NMR, HPLC |
| NMR solvent | CDCl3 |
| Calculated properties | |
|---|---|
| LogP | -11.41754 |
| Rotatable bonds | 32 |
| H bond donor | 21 |
| H bond acceptor | 33 |
| Polar surface area (PSA) | 588.27000 |
| Citations | |||||
|---|---|---|---|---|---|
| ID | Title | Year | Authors | Journal | DOI |
Bifunctional ligands that target cells displaying the αvβ3 integrin | 2007 | Owen, Robert M.; Carlson, Coby B.; Xu, Jinwang; Mowery, Patricia; Fasella, Elisabetta; Kiessling, Laura L. | ChemBioChem | ||
