Use the buttons at the bottom of Jsmol viewer to see different representations, ON/OFF Hydrogens, and ON/OFF rotation.
3D model is for representation purpose only.
.
.
Schematic representation of peptide, linker and drug in the peptide-drug conjugates
 |
 |
 |
|
 |
|---|---|---|---|---|
| FFKV | 1H-Pyrazole-5-carboxylic acid, 3-amino-1-[(4-methoxyphenyl)methyl]-methyl ester |
| Identification | |
|---|---|
| ConjuPepDB ID | cpd01157 |
| Smiles | |
| Molecular weight | 1016.5 |
| Molecular formula | C55H68N8O11 |
| Chemical name | Peptide information |
| Sequence (one letter) | FFKV |
| Length | 4 |
| Peptide name | tetrapeptide |
| External ID | |
|---|---|
| CAS number | 940964-37-4 |
| Other information | |
|---|---|
| Application | Diagnosis, fluorescence label |
| Additional function | Alzheimer's disease therapy |
| Pharmacological class | neurological |
| Conjugate type | amide |
| Linker | no |
| Small molecule | 1H-Pyrazole-5-carboxylic acid, 3-amino-1-[(4-methoxyphenyl)methyl]-methyl ester |
| Small molecule CAS | 625386-12-1 |
| Structure method | 1H NMR HPLC-MS |
| NMR solvent | CDCl3 |
| Calculated properties | |
|---|---|
| LogP | 7.48159 |
| Rotatable bonds | 29 |
| H bond donor | 6 |
| H bond acceptor | 9 |
| Polar surface area (PSA) | 246.41000 |
| Citations | |||||
|---|---|---|---|---|---|
| ID | Title | Year | Authors | Journal | DOI |
Synthesis and Binding Studies of Alzheimer Ligands on Solid Support | 2007 | Rzepecki, Petra; Geib, Nina; Peifer, Manuel; Biesemeier, Frank; Schrader, Thomas | Journal of Organic Chemistry | ||
