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Schematic representation of peptide, linker and drug in the peptide-drug conjugates
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| XNG | 2,2,8-Trimethyl-4H-1,3-dioxino[4,5-c]pyridine-5-methanol |
| Identification | |
|---|---|
| ConjuPepDB ID | cpd01139 |
| Smiles | |
| Molecular weight | 494.238 |
| Molecular formula | C23H34N4O8 |
| Chemical name | Peptide information |
| Sequence (one letter) | XNG |
| Length | 3 |
| Peptide name | tripeptide |
| External ID | |
|---|---|
| CAS number | 1032292-60-6 |
| Other information | |
|---|---|
| Application | Synthesis |
| Additional function | development of a nucleotide delivery |
| Pharmacological class | other |
| Conjugate type | amide |
| Linker | no |
| Small molecule | 2,2,8-Trimethyl-4H-1,3-dioxino[4,5-c]pyridine-5-methanol |
| Small molecule CAS | 1136-52-3 |
| Structure method | 1H NMR |
| NMR solvent | CDCl3 or DMSO |
| Calculated properties | |
|---|---|
| LogP | -0.49863 |
| Rotatable bonds | 11 |
| H bond donor | 3 |
| H bond acceptor | 7 |
| Polar surface area (PSA) | 154.18000 |
| Citations | |||||
|---|---|---|---|---|---|
| ID | Title | Year | Authors | Journal | DOI |
Synthesis of a pyridoxine-peptide based delivery system for nucleotides | 2007 | Marchand, Arnaud; Marchand, Damien; Busson, Roger; Marliere, Philipe; Herdewijn, Piet | Chemistry & Biodiversity | ||
