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Schematic representation of peptide, linker and drug in the peptide-drug conjugates
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 |
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|---|---|---|---|---|
| XRRRRRRRR | succinic acid | Phenytoin |
| Identification | |
|---|---|
| ConjuPepDB ID | cpd01120 |
| Smiles | |
| Molecular weight | 1700.98 |
| Molecular formula | C71H120N36O14 |
| Chemical name | Peptide information |
| Sequence (one letter) | XRRRRRRRR |
| Length | 9 |
| Peptide name | N/A |
| External ID | |
|---|---|
| CAS number | 1059478-92-0 |
| Other information | |
|---|---|
| Application | Wound repair |
| Additional function | increased solubility |
| Pharmacological class | other |
| Conjugate type | amide |
| Linker | N/A |
| Linker Type | succinic acid |
| Small molecule | Phenytoin |
| Small molecule CAS | 57-41-0 |
| Structure method | 1H NMR, HPLC |
| NMR solvent | CDCl3 |
| Calculated properties | |
|---|---|
| LogP | -11.19170 |
| Rotatable bonds | 59 |
| H bond donor | 35 |
| H bond acceptor | 37 |
| Polar surface area (PSA) | 875.90000 |
| Citations | |||||
|---|---|---|---|---|---|
| ID | Title | Year | Authors | Journal | DOI |
Synthesis and assessment of a novel peptide conjugate to deliver phenytoin for wound repair | 2007 | Kennedy, C. A.; Chan, F. C.; DeVocelle, M.; Meaney, C.; Bouchier-Hayes, D. J.; Kelly, J. G. | Journal of Drug Delivery Science and Technology | ||
