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Schematic representation of peptide, linker and drug in the peptide-drug conjugates
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| AFGSAFG | 4-[1-[(2,2,6,6-tetraethyl-4-methoxy-1-piperidinyl)oxy]ethyl]-benzenemethanol |
| Identification | |
|---|---|
| ConjuPepDB ID | cpd01094 |
| Smiles | |
| Molecular weight | 1042.57 |
| Molecular formula | C55H78N8O12 |
| Chemical name | Peptide information |
| Sequence (one letter) | AFGSAFG |
| Length | 7 |
| Peptide name | N/A |
| External ID | |
|---|---|
| CAS number | 1003593-19-8 |
| Other information | |
|---|---|
| Application | Biotechnology, enzymatic hydrolysis switched by temperature control |
| Pharmacological class | other |
| Conjugate type | ether |
| Linker | no |
| Small molecule | 4-[1-[(2,2,6,6-tetraethyl-4-methoxy-1-piperidinyl)oxy]ethyl]-benzenemethanol |
| Small molecule CAS | 1003593-30-3 |
| Structure method | 1H NMR |
| Calculated properties | |
|---|---|
| LogP | 3.55169 |
| Rotatable bonds | 28 |
| H bond donor | 7 |
| H bond acceptor | 11 |
| Polar surface area (PSA) | 260.93000 |
| Citations | |||||
|---|---|---|---|---|---|
| ID | Title | Year | Authors | Journal | DOI |
Reversible switching of substrate activity of poly-N-isopropylacrylamide peptide conjugates | 2007 | Molawi, Kian; Studer, Armido | Chemical Communications | ||
