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Schematic representation of peptide, linker and drug in the peptide-drug conjugates
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| AKPGKKKPGK | N-[(1,1-Dimethylethoxy)carbonyl]-3-[(3-nitro-2-pyridinyl)dithio]-L-alanine |
| Identification | |
|---|---|
| ConjuPepDB ID | cpd01083 |
| Smiles | |
| Molecular weight | 1948.94 |
| Molecular formula | C84H136N22O27S2 |
| Chemical name | Peptide information |
| Sequence (one letter) | AKPGKKKPGK |
| Length | 10 |
| Peptide name | N/A |
| External ID | |
|---|---|
| CAS number | 1008512-43-3 |
| Other information | |
|---|---|
| Application | Synthesis |
| Additional function | possible applications in tumor imaging and therapy, synthetic vaccines, beta-sheet structures |
| Pharmacological class | anticancer |
| Conjugate type | disulfide |
| Linker | no |
| Small molecule | N-[(1,1-Dimethylethoxy)carbonyl]-3-[(3-nitro-2-pyridinyl)dithio]-L-alanine |
| Small molecule CAS | 76880-29-0 |
| Structure method | 1H and 13C NMR, RP-HPLC |
| Calculated properties | |
|---|---|
| LogP | -3.54978 |
| Rotatable bonds | 54 |
| H bond donor | 14 |
| H bond acceptor | 31 |
| Polar surface area (PSA) | 636.56000 |
| Citations | |||||
|---|---|---|---|---|---|
| ID | Title | Year | Authors | Journal | DOI |
1-Ethoxyethylidene, a New Group for the Stepwise SPPS of Aminooxyacetic Acid Containing Peptides | 2008 | Foillard, Stephanie; Ohsten Rasmussen, Martin; Razkin, Jesus; Boturyn, Didier; Dumy, Pascal | Journal of Organic Chemistry | ||
