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Schematic representation of peptide, linker and drug in the peptide-drug conjugates
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 |
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|---|---|---|---|---|
| CTVALPGGYVRVCVXVX | benzyl | Paclitaxel |
| Identification | |
|---|---|
| ConjuPepDB ID | cpd01080 |
| Smiles | |
| Molecular weight | 2873.33 |
| Molecular formula | C137H192N26O38S2 |
| Chemical name | Peptide information |
| Sequence (one letter) | CTVALPGGYVRVCVXVX |
| Length | 17 |
| Peptide name | N/A |
| External ID | |
|---|---|
| CAS number | 1022094-27-4 |
| Other information | |
|---|---|
| Application | Anticancer therapy (prodrug) |
| Additional function | targeting |
| Pharmacological class | anticancer |
| Conjugate type | amide |
| Linker | N/A |
| Linker Type | benzyl |
| Small molecule | Paclitaxel |
| Small molecule CAS | 33069-62-4 |
| Calculated properties | |
|---|---|
| LogP | -1.80065 |
| Rotatable bonds | 52 |
| H bond donor | 29 |
| H bond acceptor | 36 |
| Polar surface area (PSA) | 964.20000 |
| Citations | |||||
|---|---|---|---|---|---|
| ID | Title | Year | Authors | Journal | DOI |
A cell-penetrating peptidic GRP78 ligand for tumor cell-specific prodrug therapy | 2008 | Yoneda, Yoshiyuki; Steiniger, Sebastian C. J.; Capkova, Katerina; Mee, Jenny M.; Liu, Ying; Kaufmann, Gunnar F.; Janda, Kim D. | Bioorganic & Medicinal Chemistry Letters | ||
