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Schematic representation of peptide, linker and drug in the peptide-drug conjugates
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|---|---|---|---|---|
| CPRGGSVC | PEG | Doxorubicin |
| Identification | |
|---|---|
| ConjuPepDB ID | cpd01051 |
| Smiles | |
| Molecular weight | 1589.59 |
| Molecular formula | C68H95N13O27S2 |
| Chemical name | Peptide information |
| Sequence (one letter) | CPRGGSVC |
| Length | 8 |
| Peptide name | N/A |
| External ID | |
|---|---|
| CAS number | 1144038-82-3 |
| Other information | |
|---|---|
| Application | Anticancer therapy |
| Additional function | increasing hydrophilicity |
| Pharmacological class | anticancer |
| Conjugate type | amide |
| Linker | N/A |
| Linker Type | PEG |
| Small molecule | Doxorubicin |
| Small molecule CAS | 23214-92-8 |
| Small molecule structure | |
| Structure method | HPLC and NMR |
| Calculated properties | |
|---|---|
| LogP | -8.18975 |
| Rotatable bonds | 28 |
| H bond donor | 19 |
| H bond acceptor | 30 |
| Polar surface area (PSA) | 609.38000 |
| Citations | |||||
|---|---|---|---|---|---|
| ID | Title | Year | Authors | Journal | DOI |
Effect of Modification of the Physicochemical Properties of ICAM-1-Derived Peptides on Internalization and Intracellular Distribution in the Human Leukemic Cell Line HL-60 | 2009 | Majumdar, Sumit; Tejo, Bimo A.; Badawi, Ahmed H.; Moore, David; Krise, Jeffrey P.; Siahaan, Teruna J. | Molecular Pharmaceutics | ||
