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Schematic representation of peptide, linker and drug in the peptide-drug conjugates
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| GILKEPVHGA | 9,12-Octadecadienoic acid (9Z,12Z)-, hydrazide |
| Identification | |
|---|---|
| ConjuPepDB ID | cpd00995 |
| Smiles | |
| Molecular weight | 1338.84 |
| Molecular formula | C65H110N16O14 |
| Chemical name | Peptide information |
| Sequence (one letter) | GILKEPVHGA |
| Length | 10 |
| Peptide name | N/A |
| External ID | |
|---|---|
| CAS number | 1167995-16-5 |
| Other information | |
|---|---|
| Application | Synthesis, novel ligation method (azaGly ligation) |
| Additional function | Incorporation of acid-sensitive lipid moieties |
| Pharmacological class | other |
| Conjugate type | hydrazide |
| Linker | no |
| Small molecule | 9,12-Octadecadienoic acid (9Z,12Z)-, hydrazide |
| Small molecule CAS | 29204-27-1 |
| Structure method | 1H NMR |
| NMR solvent | H2O/D2O |
| Calculated properties | |
|---|---|
| LogP | -1.60016 |
| Rotatable bonds | 48 |
| H bond donor | 15 |
| H bond acceptor | 16 |
| Polar surface area (PSA) | 458.43000 |
| Citations | |||||
|---|---|---|---|---|---|
| ID | Title | Year | Authors | Journal | DOI |
Silver-Catalyzed azaGly Ligation. Application to the Synthesis of Azapeptides and of Lipid-Peptide Conjugates | 2009 | Ollivier, Nathalie; Besret, Soizic; Blanpain, Annick; Melnyk, Oleg | Bioconjugate Chemistry | ||
