Use the buttons at the bottom of Jsmol viewer to see different representations, ON/OFF Hydrogens, and ON/OFF rotation.
3D model is for representation purpose only.
.
.
Schematic representation of peptide, linker and drug in the peptide-drug conjugates
 |
 |
 |
|
 |
|---|---|---|---|---|
| CNGRC | PEG | Pplatinum-(SP-4-2)-(1,2-Ethanediamine-κN1,κN2)[propanedioato(2-)-κO1,κO3] |
| Identification | |
|---|---|
| ConjuPepDB ID | cpd00973 |
| Smiles | |
| Inchi Key | InChIKey=LUVNNOXOWIIFSW-UHFFFAOYNA-L |
| Molecular weight | 1436.5 |
| Molecular formula | C47H83N15O20PtS2 | Peptide information |
| Sequence (one letter) | CNGRC |
| Length | 5 |
| Peptide name | N/A |
| External ID | |
|---|---|
| CAS number | 1191457-17-6 |
| Other information | |
|---|---|
| Application | Anticancer therapy |
| Additional function | Targeting |
| Pharmacological class | anticancer |
| Conjugate type | amide |
| Linker | N/A |
| Linker Type | PEG |
| Small molecule | Pplatinum-(SP-4-2)-(1,2-Ethanediamine-κN1,κN2)[propanedioato(2-)-κO1,κO3] |
| Small molecule CAS | 41666-77-7 |
| Small molecule structure | |
| Structure method | 1H NMR, HPLC |
38
| Citations | |||||
|---|---|---|---|---|---|
| ID | Title | Year | Authors | Journal | DOI |
Peptide Targeting of Platinum Anti-Cancer Drugs | 2009 | Ndinguri, Margaret W.; Solipuram, Rajasree; Gambrell, Robert P.; Aggarwal, Sita; Hammer, Robert P. | Bioconjugate Chemistry | ||
