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Schematic representation of peptide, linker and drug in the peptide-drug conjugates
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|---|---|---|---|---|
| AFG | N-Norgalanthamine |
| Identification | |
|---|---|
| ConjuPepDB ID | cpd00956 |
| Smiles | |
| Molecular weight | 706.232 |
| Molecular formula | C37H40Cl2N4O6 |
| Chemical name | Peptide information |
| Sequence (one letter) | AFG |
| Length | 3 |
| Peptide name | tripeptide |
| External ID | |
|---|---|
| CAS number | 1197472-66-4 |
| Other information | |
|---|---|
| Application | Alzheimer's disease therapy |
| Pharmacological class | neurological |
| Conjugate type | amide |
| Linker | no |
| Small molecule | N-Norgalanthamine |
| Small molecule CAS | 41303-74-6 |
| Structure method | RP-HPLC and 1H and 13C NMR |
| Calculated properties | |
|---|---|
| LogP | 4.54290 |
| Rotatable bonds | 12 |
| H bond donor | 3 |
| H bond acceptor | 7 |
| Polar surface area (PSA) | 118.23000 |
| Citations | |||||
|---|---|---|---|---|---|
| ID | Title | Year | Authors | Journal | DOI |
Synthesis and Characterization of New Galanthamine Derivatives Comprising Peptide Moiety | 2009 | Lyubomir T. Vezenkov, Maria G. Georgieva, Dantcho L. Danalev, Tchavdar B. Ivanov, Galya I. Ivanova | Protein & Peptide Letters | ||
