3D model is for representation purpose only.
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XKKX | triazole | alkyne-functionalized cysteine protease inhibitor L1 |
Identification | |
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ConjuPepDB ID | cpd00925 |
Smiles | |
Inchi Key | InChIKey=RWUHCTFQFARTMA-QQVWZEJNSA-N |
Molecular weight | 1012.66 |
Molecular formula | C54H84N12O7 |
Chemical name | Peptide information |
Sequence (one letter) | XKKX |
Length | 4 |
Peptide name | KK (plasma membrane delivery) |
External ID | |
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CAS number | 1258942-82-3 |
Other information | |
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Application | Synthesis and inhibition of lysosomal cysteine proteases |
Additional function | Potential improvement of in vivo drug efficacy |
Conjugate type | triazole |
Linker | N/A |
Linker Type | triazole |
Small molecule | alkyne-functionalized cysteine protease inhibitor L1 |
Small molecule CAS | 1258942-76-5 |
Small molecule structure | |
Calculated properties | |
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LogP | 5.87109 |
Rotatable bonds | 40 |
H bond donor | 6 |
H bond acceptor | 12 |
Polar surface area (PSA) | 272.79000 |
Citations | |||||
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ID | Title | Year | Authors | Journal | DOI |
"Click" synthesis of small molecule-peptide conjugates for organelle-specific delivery and inhibition of lysosomal cysteine proteases" | 2010 | Loh, Yuhui; Shi, Haibin; Hu, Mingyu; Yao, Shao Q. | Chemical Communications |