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View Conjugates details

ConjuPepDB ID: cpd00891

Chemical structure


molecule
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cpd00891


Schematic Help Icon Schematic representation of peptide, linker and drug in the peptide-drug conjugates
WAAW Kanamycin A derivative
Identification
ConjuPepDB ID

cpd00891

Smiles
Inchi Key

InChIKey=LMUMCBVXZUBGQJ-CXLTXAHCSA-N

Molecular weight

2910.39

Molecular formula

C140H199N21O46

Chemical name
Peptide information
Sequence (one letter)

WAAW

Length

4

Peptide name

tetrapeptide

External ID
CAS number

1134204-89-9

Other information
Application

Antimicrobial therapy, antibacterial (P. aeruginosa)

Additional function

Overcome drug resistance

Conjugate type

triazole

Linker

no

Small molecule

Kanamycin A derivative

Small molecule CAS

953395-50-1

Small molecule structure

Calculated properties
LogP

6.39164

Rotatable bonds

63

H bond donor

25

H bond acceptor

39

Polar surface area (PSA)

901.85000

Citations
ID Title Year Authors Journal DOI

Cpdart0126

Evaluation of amphiphilic aminoglycoside-peptide triazole conjugates as antibacterial agents

2010

Bera, Smritilekha; Zhanel, George G.; Schweizer, Frank

Bioorganic & Medicinal Chemistry

..