Use the buttons at the bottom of Jsmol viewer to see different representations, ON/OFF Hydrogens, and ON/OFF rotation.
3D model is for representation purpose only.
.
.
Schematic representation of peptide, linker and drug in the peptide-drug conjugates
 |
 |
 |
|
 |
|---|---|---|---|---|
| VPVP | Cytarabine |
| Identification | |
|---|---|
| ConjuPepDB ID | cpd00880 | Peptide information |
| Sequence (one letter) | VPVP |
| Length | 4 |
| Peptide name | tetrapeptide |
| External ID | |
|---|---|
| CAS number | 1203578-27-1 |
| Other information | |
|---|---|
| Application | Synthesis |
| Additional function | Increase solubility of drug molecules and/or to allow better formulation properties |
| Conjugate type | amide |
| Linker | no |
| Small molecule | Cytarabine |
| Small molecule CAS | 147-94-4 |
| Small molecule structure | |
| Structure method | 1H- and 13C-NMR |
| NMR solvent | DMSO-d6 or acetone-d6 |
| Citations | |||||
|---|---|---|---|---|---|
| ID | Title | Year | Authors | Journal | DOI |
Application of the Dipeptidyl Peptidase IV (DPPIV/CD26) Based Prodrug Approach to Different Amine-Containing Drugs | 2010 | Diez-Torrubia, Alberto; Garcia-Aparicio, Carlos; Cabrera, Silvia; De Meester, Ingrid; Balzarini, Jan; Camarasa, Maria-Jose; Velazquez, Sonsoles | Journal of Medicinal Chemistry | ||
