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ConjuPepDB ID: cpd00805

Chemical structure


molecule
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cpd00805


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GRPAK p-Toluenesulfonamide
Identification
ConjuPepDB ID

cpd00805

Smiles
Inchi Key

InChIKey=IEYGESXSSLCIHI-UKTKCLSNNA-N

Molecular weight

905.411

Molecular formula

C44H59N9O10S

Chemical name
Peptide information
Sequence (one letter)

GRPAK

Length

5

Peptide name

pentapeptide generated by plasmin degradation from the fibrinogen beta chain

External ID
CAS number

860020-51-5

Other information
Application

Anti-thrombolytic therapy

Additional function

Free radical scavenging and thrombolitic activity, protective effect against organ injury induced by I/R in rat

Conjugate type

sulfonamide

Linker

no

Small molecule

p-Toluenesulfonamide

Small molecule CAS

70-55-3

Small molecule structure

NMR solvent

CD3OD + TFA

Calculated properties
LogP

1.97045

Rotatable bonds

24

H bond donor

7

H bond acceptor

11

Polar surface area (PSA)

282.81000

Citations
ID Title Year Authors Journal DOI

Cpdart0119

A new class of β-carboline alkaloid-peptide conjugates with therapeutic efficacy in acute limb ischemia/reperfusion injury

2011

Bi, Wei; Bi, Yue; Xue, Ping; Zhang, Yanrong; Gao, Xiang; Wang, Zhibo; Li, Meng; Baudy-Floc'h, Michele; Ngerebara, Nathaniel; Michael Gibson, K.; Bi, Lanrong

European Journal of Medicinal Chemistry

..