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Schematic representation of peptide, linker and drug in the peptide-drug conjugates
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| XWKWX | C-5’’-modified neomycin B analog |
| Identification | |
|---|---|
| ConjuPepDB ID | cpd00741 |
| Smiles | |
| Inchi Key | InChIKey=HUEUSIGMMQMKAS-DNZUYCEUSA-N |
| Molecular weight | 2579.22 |
| Molecular formula | C130H178N12O42 |
| Chemical name | Peptide information |
| Sequence (one letter) | XWKWX |
| Length | 5 |
| Peptide name | tripeptide |
| External ID | |
|---|---|
| CAS number | 1292767-08-8 |
| Other information | |
|---|---|
| Application | Antomicrobial therapy, antibacterial (P. Aeruginosa) |
| Additional function | Improve activity |
| Conjugate type | carbamoyl |
| Linker | no |
| Small molecule | C-5’’-modified neomycin B analog |
| Small molecule CAS | 241820-92-8 |
| Small molecule structure | |
| Calculated properties | |
|---|---|
| LogP | 14.62555 |
| Rotatable bonds | 67 |
| H bond donor | 9 |
| H bond acceptor | 25 |
| Polar surface area (PSA) | 657.99000 |
| Citations | |||||
|---|---|---|---|---|---|
| ID | Title | Year | Authors | Journal | DOI |
Synthesis and antibacterial activity of amphiphilic lysine-ligated neomycin B conjugates | 2011 | Bera, Smritilekha; Zhanel, George G.; Schweizer, Frank | Carbohydrate Research | ||
