conjupepdb_log

View Conjugates details

ConjuPepDB ID: cpd00721

Chemical structure


molecule
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cpd00721


Schematic Help Icon Schematic representation of peptide, linker and drug in the peptide-drug conjugates
GEGFPGVGVPGVGVPGVGVPGFGFPGFGFP 3-(4-piperidyl)-6-fluoro-1,2-benzisoxazole
Identification
ConjuPepDB ID

cpd00721

Smiles
Inchi Key

InChIKey=AXITYBPIXCMJTH-OEMJBEGNSA-N

Molecular weight

3127.6

Molecular formula

C157H215FN32O35

Chemical name
Peptide information
Sequence (one letter)

GEGFPGVGVPGVGVPGVGVPGFGFPGFGFP

Length

30

Peptide name

elastin (fragment)

External ID
CAS number

1270202-39-5

Other information
Application

Antomicrobial therapy, antibacterial (C. staphylococcus, K. pneumoniae) and antifungal (A. niger, A. flavus and F. oxysporum)

Additional function

Increase effect and enhance biocompatibility

Conjugate type

amide

Linker

no

Small molecule

3-(4-piperidyl)-6-fluoro-1,2-benzisoxazole

Small molecule CAS

84163-13-3

Small molecule structure

Structure method

1H-NMR

NMR solvent

CDCl3

Calculated properties
LogP

-3.06862

Rotatable bonds

78

H bond donor

24

H bond acceptor

33

Polar surface area (PSA)

902.13000

Citations
ID Title Year Authors Journal DOI

Cpdart0114

Synthesis of elastin based peptides conjugated to benzisoxazole as a new class of potent antimicrobials - A novel approach to enhance biocompatibility

2011

Suhas, R.; Chandrashekar, S.; Gowda, D. Channe

European Journal of Medicinal Chemistry

..