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Schematic representation of peptide, linker and drug in the peptide-drug conjugates
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| GEGFPGVGVPGVGFPGFGFPGVGVPGVGFP | 1-(2,3-Dichlorophenyl)piperazine |
| Identification | |
|---|---|
| ConjuPepDB ID | cpd00648 |
| Smiles | |
| Inchi Key | InChIKey=OMGUENYIWSTBDN-UXQGFBHDSA-N |
| Molecular weight | 3137.54 |
| Molecular formula | C155H214Cl2N32O34 |
| Chemical name | Peptide information |
| Sequence (one letter) | GEGFPGVGVPGVGFPGFGFPGVGVPGVGFP |
| Length | 30 |
| Peptide name | elastin-base peptide |
| External ID | |
|---|---|
| CAS number | 1355063-26-1 |
| Other information | |
|---|---|
| Application | Antimicrobial therapy, antifungal (Aspergillus and Fusarium) |
| Additional function | Improved activity, potential lead for antimicrobial agents |
| Conjugate type | amide |
| Linker | no |
| Small molecule | 1-(2,3-Dichlorophenyl)piperazine |
| Small molecule CAS | 41202-77-1 |
| Small molecule structure | |
| Structure method | 1H-NMR |
| NMR solvent | CDCl3 |
| Calculated properties | |
|---|---|
| LogP | -2.04949 |
| Rotatable bonds | 78 |
| H bond donor | 24 |
| H bond acceptor | 33 |
| Polar surface area (PSA) | 879.34000 |
| Citations | |||||
|---|---|---|---|---|---|
| ID | Title | Year | Authors | Journal | DOI |
A New Family of Highly Potent Inhibitors of Microbes: Synthesis and Conjugation of Elastin Based Peptides to Piperazine Derivative | 2012 | Suhas, R.; Chandrashekar, S.; Gowda, D. Channe | International Journal of Peptide Research and Therapeutics | ||
