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Schematic representation of peptide, linker and drug in the peptide-drug conjugates
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|---|---|---|---|---|
| XAR | Caffeic acid |
| Identification | |
|---|---|
| ConjuPepDB ID | cpd00627 |
| Smiles | |
| Inchi Key | InChIKey=GJWIRYKPOXHCDZ-JQWIXIFHSA-N |
| Molecular weight | 407.18 |
| Molecular formula | C18H25N5O6 |
| Chemical name | Peptide information |
| Sequence (one letter) | XAR |
| Length | 3 |
| Peptide name | melanocortin receptor 1 (MC1R) antagonist peptide |
| External ID | |
|---|---|
| CAS number | 1433981-77-1 |
| Other information | |
|---|---|
| Application | Synthesis, melanogenesis inhibition (melanocortin receptor 1 (MC1R) anatonists) |
| Additional function | Possible treatment for hyperpigmentation, |
| Conjugate type | amide |
| Linker | no |
| Small molecule | Caffeic acid |
| Small molecule CAS | 331-39-5 |
| Small molecule structure | |
| Calculated properties | |
|---|---|
| LogP | -2.15474 |
| Rotatable bonds | 10 |
| H bond donor | 7 |
| H bond acceptor | 9 |
| Polar surface area (PSA) | 200.36000 |
| Citations | |||||
|---|---|---|---|---|---|
| ID | Title | Year | Authors | Journal | DOI |
Synthesis of small molecule-peptide conjugates as potential whitening agents | 2012 | Lee, Hye-Suk; Shin, Kyong-Hoon; Ryu, Geun-Seok; Chi, Gyeong-Yup; Cho, In-Shik; Kim, Han-Young | Bulletin of the Korean Chemical Society | ||
