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Schematic representation of peptide, linker and drug in the peptide-drug conjugates
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| GLS | 1,5,9-Triazacyclododecane-1-acetic acid |
| Identification | |
|---|---|
| ConjuPepDB ID | cpd00602 |
| Smiles | |
| Inchi Key | InChIKey=SDSVHHNDESHKCU-ZEQRLZLVSA-N |
| Molecular weight | 643.416 |
| Molecular formula | C31H57N5O9 |
| Chemical name | Peptide information |
| Sequence (one letter) | GLS |
| Length | 3 |
| Peptide name | tripeptide |
| External ID | |
|---|---|
| CAS number | 1367281-23-9 |
| Other information | |
|---|---|
| Application | Synthesis |
| Additional function | DNA cleaving, metal-free |
| Conjugate type | amine |
| Linker | no |
| Small molecule | 1,5,9-Triazacyclododecane-1-acetic acid |
| Small molecule CAS | 1334610-50-2 |
| Small molecule structure | |
| Structure method | 1H- and 13C-NMR |
| Calculated properties | |
|---|---|
| LogP | 0.79414 |
| Rotatable bonds | 14 |
| H bond donor | 3 |
| H bond acceptor | 7 |
| Polar surface area (PSA) | 167.05000 |
| Citations | |||||
|---|---|---|---|---|---|
| ID | Title | Year | Authors | Journal | DOI |
Synthesis of [12]aneN3-dipeptide conjugates as metal-free DNA nucleases | 2012 | Li, Zhi-Fen; Chen, Hua-Long; Zhang, Li-Jun; Lu, Zhong-Lin | Bioorganic & Medicinal Chemistry Letters | ||
