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Schematic representation of peptide, linker and drug in the peptide-drug conjugates
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| XVVXX | β-D-Galactopyranoside derivative |
| Identification | |
|---|---|
| ConjuPepDB ID | cpd00568 |
| Smiles | |
| Inchi Key | InChIKey=OKJSDVVAYXRCJJ-SFFXIIEVSA-N |
| Molecular weight | 1112.59 |
| Molecular formula | C56H84N6O17 |
| Chemical name | Peptide information |
| Sequence (one letter) | XVVXX |
| Length | 5 |
| Peptide name | dipeptide |
| External ID | |
|---|---|
| CAS number | 1418735-55-3 |
| Other information | |
|---|---|
| Application | Anticancer therapy |
| Additional function | Targeting beta-galactosidase expressing cells |
| Conjugate type | carbamate |
| Linker | no |
| Small molecule | β-D-Galactopyranoside derivative |
| Small molecule CAS | 1313026-27-5 |
| Small molecule structure | |
| Calculated properties | |
|---|---|
| LogP | 3.41194 |
| Rotatable bonds | 28 |
| H bond donor | 7 |
| H bond acceptor | 16 |
| Polar surface area (PSA) | 312.25000 |
| Citations | |||||
|---|---|---|---|---|---|
| ID | Title | Year | Authors | Journal | DOI |
The First Generation of β‐Galactosidase‐Responsive Prodrugs Designed for the Selective Treatment of Solid Tumors in Prodrug Monotherapy | 2012 | Legigan, Thibaut; Clarhaut, Jonathan; Tranoy-Opalinski, Isabelle; Monvoisin, Arnaud; Renoux, Brigitte; Thomas, Mikael; Le Pape, Alain; Lerondel, Stephanie; Papot, Sebastien | Angewandte Chemie, International Edition | ||
