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CKKWKMRRNQFWIKIQR | Fluorene-9-methanol |
Identification | |
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ConjuPepDB ID | cpd00539 |
Smiles | |
Inchi Key | InChIKey=CKYIKYSOOLLZJA-LKBPDKPESA-N |
Molecular weight | 2501.3 |
Molecular formula | C112H176N38O22S3 |
Chemical name | Peptide information |
Sequence (one letter) | CKKWKMRRNQFWIKIQR |
Length | 17 |
Peptide name | penetratin (fragment) |
External ID | |
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CAS number | 1433417-45-8 |
Other information | |
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Application | Anticancer therapy, PKC inhibition |
Additional function | Possible strategy for selective, cell-penetrating kinase inhibitor against cancer, immunological disorders, and neurodegenerative diseases |
Pharmacological class | anticancer |
Conjugate type | disulfide |
Linker | no |
Small molecule | Fluorene-9-methanol |
Small molecule CAS | 24324-17-2 |
Small molecule structure | |
Calculated properties | |
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LogP | -7.18105 |
Rotatable bonds | 87 |
H bond donor | 33 |
H bond acceptor | 37 |
Polar surface area (PSA) | 1051.55000 |
Citations | |||||
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ID | Title | Year | Authors | Journal | DOI |
Cell-Penetrating Bisubstrate-Based Protein Kinase C Inhibitors | 2013 | van Wandelen, Loek T. M.; van Ameijde, Jeroen; Ismail-Ali, Ahmed F.; van Ufford, H. C. Quarles; Vijftigschild, Lodewijk A. W.; Beekman, Jeffrey M.; Martin, Nathaniel I.; Ruijtenbeek, Rob; Liskamp, Rob M. J. | ACS Chemical Biology |